A Computational Model for Simulating Continuous Time Boolean Networks
نویسندگان
چکیده
Random Boolean networks are among the most popular model systems used for modelling the gene regulatory networks due to their answering of the many biological questions in a realistic way, insights into the overall behavior of large genetic networks and suitability for inference. However, discrete time Boolean networks have serious limitations in simulating non-repeating complex dynamic systems and incorporating the biochemical information on the reaction rates. In this work we introduce continuous-time Boolean network structure to simulate the genomic regulation as a binary complex dynamic system, discuss their potential of solving the problems of the conventional discrete time Boolean networks and develop a framework for simulating continuous time Boolean networks.
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